BT-066 · Apocynaceae

Oleander

Nerium oleander
Evidence: TraditionalHigh risk

Even using oleander twigs as skewers or barbecue wood can poison people; care is needed at picnics.

Other names
Adelfa, zakkum (Turkish)
Part used
Leaves (historical only)
Region
Anatolia and the Mediterranean
Use
Poisonous, Healing
Oleander (Nerium oleander): pink flowers
Photo: CC BY 2.5 · Wikimedia Commons
In short

What is Oleander?

Oleander (Nerium oleander) is a plant of the Apocynaceae family. Traditions that use it: Anatolia and the Mediterranean. Part used: leaves (historical only).

What is Oleander used for?

Traditional use: In folk use the leaves were boiled for haemorrhoids, skin disease and cancer. Scientific evidence: traditional. Contains cardiac glycosides such as oleandrin, which disrupt heart rhythm.

Is Oleander safe?

Safety label: high risk. Every part of the plant is deadly poisonous; even a few leaves are dangerous. Burning the branches on a barbecue or using them as skewers can also cause poisoning.

Traditional use

Anatolia

In folk use the leaves were boiled for haemorrhoids, skin disease and cancer. These uses caused fatal poisonings.

Mediterranean

A common ornamental on coasts and road medians.

In nature

Where it grows
Stream beds in the Mediterranean and Aegean; ornamental in cities.
Harvest season
Not to be collected. Flowers May–October.
Local names
zakkum, ağı ağacı, ağu çiçeği, zıkkım

Mix-up risk

Its leaves can be mistaken for bay or willow; poisonings have happened when used instead of bay leaves.

Preparation

Never prepare or drink it in any form.

What science says

Contains cardiac glycosides such as oleandrin, which disrupt heart rhythm. Studies on its use for cancer have shown no benefit.

Safety

High risk

Every part of the plant is deadly poisonous; even a few leaves are dangerous. Burning the branches on a barbecue or using them as skewers can also cause poisoning.

Drug interactions

Medicine or substanceWhy it matters
Digoxin and heart medicinesOleandrin acts like digoxin; together they can cause fatal heart rhythm disturbance.
Diuretics, laxatives, licoriceLower potassium and worsen poisoning.

This list is not complete. If you take regular medication, ask your pharmacist or doctor before trying Oleander.

Similar plants

Sources

  1. ResearchHuman Deaths Related to Oleander Poisoning: A Review of the Literature
  2. ResearchOleander and Datura Poisoning: An Update
  3. BookBaytop T. Türkiye’de Bitkiler ile Tedavi: Geçmişte ve Bugün. 2. baskı. İstanbul: Nobel Tıp Kitabevleri; 1999.
  4. Botanical recordKew Plants of the World Online: Nerium oleander
  5. Titles of research sources are summarised in Turkish on the Turkish page; links open the original English publications.

Written by Edanaz Tınmazlar · Last reviewed: · Türkçe