BT-042 · Rubiaceae

Cinchona

Cinchona officinalis
Evidence: ClinicalHigh risk

The cinchona tree appears on Peru’s coat of arms, standing for the country’s plant wealth.

Other names
Quinine tree, cascarilla, quina, kınakına (Turkish)
Part used
Bark
Region
Andes
Use
Healing, Poisonous
Cinchona (Cinchona officinalis): leafy branches
Photo: James Steakley · CC BY-SA 3.0 · Wikimedia Commons
In short

What is Cinchona?

Cinchona (Cinchona officinalis) is a plant of the Rubiaceae family. Traditions that use it: Andes. Part used: bark.

What is Cinchona used for?

Traditional use: Grows in the Andean cloud forests. Scientific evidence: clinical. The quinine in its bark was the main malaria drug for centuries.

Is Cinchona safe?

Safety label: high risk. Do not use the bark or quinine on your own: it can cause ringing in the ears, hearing loss, heart rhythm problems and blood disorders (cinchonism). The amount in tonic water is very low.

Traditional use

Andes

Grows in the Andean cloud forests. The bark is said to have been used against shivering and fever.

Europe

In the 17th century Jesuit priests brought the bark to Europe; as “Jesuit’s powder” it became the first effective malaria medicine.

In nature

Where it grows
Andean cloud forests at 1,500–2,700 m (Ecuador, Peru).
Harvest season
Bark is collected all year.
Local names
kınakına, kına kına, kinin ağacı; local names cascarilla, quina

Mix-up risk

“Cinchona” covers several species with different quinine levels.

Preparation

Not recommended to prepare at home.

What science says

The quinine in its bark was the main malaria drug for centuries. Artemisinin and synthetic drugs have largely replaced it, but it is still used in some cases.

Safety

High risk

Do not use the bark or quinine on your own: it can cause ringing in the ears, hearing loss, heart rhythm problems and blood disorders (cinchonism). The amount in tonic water is very low.

Drug interactions

Medicine or substanceWhy it matters
Heart rhythm drugs and drugs that prolong the QT intervalRisk of dangerous heart rhythm disturbance.
Blood thinnersIncreases bleeding risk.
Diabetes medicinesCan lower blood sugar.
Mefloquine and other malaria drugsHeart and nervous system side effects multiply.

This list is not complete. If you take regular medication, ask your pharmacist or doctor before trying Cinchona.

Conservation

Note
Overcut for its bark in colonial times; wild populations are still under pressure today.

Culture bridge

Two traditions that beat malaria. The Andes’ cinchona bark and Asia’s wormwood became the two cornerstones of modern malaria treatment. Read the comparison →

Similar plants

Sources

  1. ResearchQuinine, an old anti-malarial drug in a modern world: role in the treatment of malaria
  2. ResearchDiscovery of Cinchona as Antimalarial, Viceroyalty of Peru, circa 1630
  3. Botanical recordKew Plants of the World Online: Cinchona officinalis
  4. Titles of research sources are summarised in Turkish on the Turkish page; links open the original English publications.

Written by Edanaz Tınmazlar · Last reviewed: · Türkçe