Sangre de grado
Croton lechleriApplied to the skin, the red resin turns white and forms a thin film; in the Amazon it is called a liquid bandage.

What is Sangre de grado?
Sangre de grado (Croton lechleri) is a plant of the Euphorbiaceae family. Traditions that use it: Amazon. Part used: red resin (latex).
What is Sangre de grado used for?
Traditional use: When the bark is cut, a blood-red sap flows. Scientific evidence: limited. Crofelemer, developed from the resin, was approved in the US in 2012 for diarrhoea in people with HIV, the first oral botanical drug approved there.
Is Sangre de grado safe?
Safety label: generally safe. Generally safe on the skin. Safety data for drinking it are limited; not for use in pregnancy.
Traditional use
When the bark is cut, a blood-red sap flows. It is applied to wounds, insect bites and mouth sores; a few drops in water are drunk for diarrhoea and the stomach.
In nature
Mix-up risk
“Dragon’s blood” is also used for Dracaena and Daemonorops resins, which are entirely different plants.
Preparation
The resin is applied directly to the skin.
What science says
Crofelemer, developed from the resin, was approved in the US in 2012 for diarrhoea in people with HIV, the first oral botanical drug approved there. Its wound-healing effect has been shown in lab and animal studies.
Safety
Generally safe on the skin. Safety data for drinking it are limited; not for use in pregnancy.
Similar plants
Sources
- Official sourceABD FDA: MYTESI (crofelemer) prescribing information, ilk onay 2012
- ResearchA Review on Phytochemistry and Recent Pharmacology of Dragon’s Blood (Croton lechleri)
- Botanical recordKew Plants of the World Online: Croton lechleri
- Titles of research sources are summarised in Turkish on the Turkish page; links open the original English publications.
Written by Edanaz Tınmazlar · Last reviewed: · Türkçe


